PROFILE study
Do you have a family history of prostate cancer? Would you be interested in taking part in a research study investigating the role genetic testing could play in the development of prostate cancer screening programmes?
The PROFILE study follows years of research into prostate cancer risk factors, including the discovery of 31 genetic variants that predispose to the disease, and the recognition that family history substantially increases men’s chances of developing the disease.
The study will compare rates of prostate cancer diagnosis among men considered to be in different risk categories, based on the results of genetic testing.
To take part in the study you will need to between the ages of 40 and 69 years and have a family history of prostate cancer (but have not had prostate cancer yourself). A family history of prostate cancer is defined as having a father, son or brother diagnosed with prostate cancer before the age of 70 years, having two relatives from the same side of the family diagnosed with prostate cancer where one relative was diagnosed before the age of 70 or having three relatives on the same side of the family diagnosed with prostate cancer at any age.
Men taking part will have some prostate cancer screening tests, including a biopsy, and possibly an MRI scan. They will give permission for researchers to study blood, tissue and urine samples.
If you are interested in finding out more please contact the study coordinator, Elizabeth Bancroft on 0207 808 2136 or elizabeth.bancroft@rmh.nhs.uk.
